C-C chemokine receptor type 6 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P51684. Use UniProt P51684 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P51684 as the stable identity anchor, then attach disease evidence before program review.
C-C chemokine receptor type 6
Review this target as C-C chemokine receptor type 6, mapped to UniProt P51684. Sequence length is 374 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats C-C chemokine receptor type 6 as ChEMBL target CHEMBL4423, mapped to UniProt P51684. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether C-C chemokine receptor type 6 is the right protein anchor across sources, using UniProt P51684 as the stable mapping.
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| Preferred Name | C-C chemokine receptor type 6 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P51684 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | C-C chemokine receptor type 6 |
| UniProt Accession | P51684 |
| Component Type | Protein |
| Sequence Length | 374 aa |
C-C chemokine receptor type 6
Review this target as C-C chemokine receptor type 6, mapped to UniProt P51684. Sequence length is 374 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5517631 | 9.21 | IC50 | 0.62 | Preclinical |
| CHEMBL3704570 | 8.85 | IC50 | 1.4 | Preclinical |
| CHEMBL6049426 | 8.8 | IC50 | 1.6 | Preclinical |
| CHEMBL3704573 | 8.72 | IC50 | 1.9 | Preclinical |
| CHEMBL5979255 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL3952996 | 8.66 | IC50 | 2.2 | Preclinical |
| CHEMBL5561521 | 8.54 | IC50 | 2.9 | Preclinical |
| CHEMBL3701196 | 8.47 | IC50 | 3.4 | Preclinical |
| CHEMBL3701188 | 8.24 | IC50 | 5.8 | Preclinical |
| CHEMBL3951994 | 8.22 | IC50 | 6.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 18 | 82 | 6.9 |
| assay format | 7 | 218 | 4.6 |
| single protein format | 3 | 0 | — |
| tissue-based format | 3 | 1 | 8.0 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 17 | 0 | — |
| cell-based format | 4 | 8 | 8.2 |
| assay format | 1 | 119 | 7.0 |