Retinoic acid receptor RXR-alpha · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-13Protein identity stays anchored to UniProt Q05343. Use UniProt Q05343 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q05343 as the stable identity anchor, then attach disease evidence before program review.
Retinoic acid receptor RXR-alpha
Review this target as Retinoic acid receptor RXR-alpha, mapped to UniProt Q05343. Sequence length is 467 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Retinoic acid receptor RXR-alpha as ChEMBL target CHEMBL4431, mapped to UniProt Q05343. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Retinoic acid receptor RXR-alpha |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | Q05343 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Retinoic acid receptor RXR-alpha |
| UniProt Accession | Q05343 |
| Component Type | Protein |
| Sequence Length | 467 aa |
Retinoic acid receptor RXR-alpha
Review this target as Retinoic acid receptor RXR-alpha, mapped to UniProt Q05343. Sequence length is 467 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL340074 | 9.05 | Ki | 0.9 | Preclinical |
| CHEMBL337719 | 9.0 | Ki | 1.0 | Preclinical |
| CHEMBL133176 | 8.72 | Ki | 1.9 | Preclinical |
| CHEMBL336086 | 8.72 | Ki | 1.9 | Preclinical |
| CHEMBL335762 | 8.72 | Ki | 1.9 | Preclinical |
| CHEMBL340555 | 8.66 | Ki | 2.2 | Preclinical |
| CHEMBL337719 | 8.64 | IC50 | 2.3 | Preclinical |
| CHEMBL42314 | 8.52 | Ki | 3.0 | Preclinical |
| CHEMBL129887 | 8.49 | Ki | 3.2 | Preclinical |
| CHEMBL336086 | 8.48 | IC50 | 3.3 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 10 | 26 | 7.4 |
| single protein format | 1 | 17 | 8.3 |