Large neutral amino acids transporter small subunit 1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q01650. Use UniProt Q01650 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q01650 as the stable identity anchor, then attach disease evidence before program review.
Large neutral amino acids transporter small subunit 1
Review this target as Large neutral amino acids transporter small subunit 1, mapped to UniProt Q01650. Sequence length is 507 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Large neutral amino acids transporter small subunit 1 as ChEMBL target CHEMBL4459, mapped to UniProt Q01650. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Large neutral amino acids transporter small subunit 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q01650 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Large neutral amino acids transporter small subunit 1 |
| UniProt Accession | Q01650 |
| Component Type | Protein |
| Sequence Length | 507 aa |
Large neutral amino acids transporter small subunit 1
Review this target as Large neutral amino acids transporter small subunit 1, mapped to UniProt Q01650. Sequence length is 507 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4538666 | 7.22 | IC50 | 60.0 | Preclinical |
| CHEMBL4526588 | 6.01 | IC50 | 980.0 | Preclinical |
| CHEMBL5653589 | 5.92 | Kd | 1189.41 | Preclinical |
| CHEMBL3752910 | 5.65 | Kd | 2219.04 | Preclinical |
| CHEMBL4642431 | 5.46 | IC50 | 3480.0 | Preclinical |
| CHEMBL58129 | 5.18 | IC50 | 6600.0 | Preclinical |
| CHEMBL3809112 | 5.14 | IC50 | 7300.0 | Preclinical |
| CHEMBL3809645 | 5.04 | IC50 | 9100.0 | Preclinical |
| CHEMBL5896366 | 4.98 | IC50 | 10400.0 | Preclinical |
| CHEMBL4248463 | 4.77 | IC50 | 17000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 64 | 55 | 4.6 |
| single protein format | 6 | 3 | 5.9 |
| assay format | 1 | 17 | 4.3 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 9 | 0 | — |