Platelet-activating factor acetylhydrolase IB subunit alpha2 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P68402. Use UniProt P68402 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P68402 as the stable identity anchor, then attach disease evidence before program review.
Platelet-activating factor acetylhydrolase IB subunit alpha2
Review this target as Platelet-activating factor acetylhydrolase IB subunit alpha2, mapped to UniProt P68402. Sequence length is 229 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Platelet-activating factor acetylhydrolase IB subunit alpha2 as ChEMBL target CHEMBL4463, mapped to UniProt P68402. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Platelet-activating factor acetylhydrolase IB subunit alpha2 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P68402 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Platelet-activating factor acetylhydrolase IB subunit alpha2 |
| UniProt Accession | P68402 |
| Component Type | Protein |
| Sequence Length | 229 aa |
Platelet-activating factor acetylhydrolase IB subunit alpha2
Review this target as Platelet-activating factor acetylhydrolase IB subunit alpha2, mapped to UniProt P68402. Sequence length is 229 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL113262 | 7.14 | IC50 | 72.0 | Preclinical |
| CHEMBL3827161 | 5.52 | IC50 | 3000.0 | Preclinical |
| CHEMBL3828405 | 5.52 | IC50 | 3000.0 | Preclinical |
| CHEMBL3827226 | 5.4 | IC50 | 4000.0 | Preclinical |
| CHEMBL3827685 | 5.4 | IC50 | 4000.0 | Preclinical |
| CHEMBL3827906 | 5.4 | IC50 | 4000.0 | Preclinical |
| CHEMBL3828611 | 5.3 | IC50 | 5000.0 | Preclinical |
| CHEMBL3828744 | 5.0 | IC50 | 10000.0 | Preclinical |
| CHEMBL3827742 | 4.8 | IC50 | 16000.0 | Preclinical |
| CHEMBL3828121 | 4.47 | IC50 | 34000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 13 | 11 | 5.1 |
| cell-based format | 6 | 1 | 5.5 |