Trypsin II · SINGLE PROTEIN · Bos taurus
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As of 2026-09-13Protein identity stays anchored to UniProt Q29463. Use UniProt Q29463 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q29463 as the stable identity anchor, then attach disease evidence before program review.
Anionic trypsin
Review this target as Trypsin II, mapped to UniProt Q29463. ChEMBL maps the protein component as Anionic trypsin. Sequence length is 247 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Trypsin II as ChEMBL target CHEMBL4472, mapped to UniProt Q29463. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Trypsin II |
| Target Type | SINGLE PROTEIN |
| Organism | Bos taurus |
| UniProt | Q29463 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Anionic trypsin |
| UniProt Accession | Q29463 |
| Component Type | Protein |
| Sequence Length | 247 aa |
Anionic trypsin
Review this target as Trypsin II, mapped to UniProt Q29463. ChEMBL maps the protein component as Anionic trypsin. Sequence length is 247 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL141676 | 8.92 | IC50 | 1.2 | Preclinical |
| CHEMBL332121 | 7.92 | Ki | 12.0 | Preclinical |
| CHEMBL320393 | 7.7 | Ki | 20.0 | Preclinical |
| CHEMBL322437 | 7.66 | Ki | 22.0 | Preclinical |
| CHEMBL319227 | 7.58 | EC50 | 26.0 | Preclinical |
| CHEMBL104970 | 7.57 | Ki | 27.0 | Preclinical |
| CHEMBL322622 | 7.55 | Ki | 28.0 | Preclinical |
| CHEMBL322901 | 7.36 | Ki | 44.0 | Preclinical |
| CHEMBL450936 | 7.31 | Ki | 49.0 | Preclinical |
| CHEMBL326013 | 7.19 | Ki | 64.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 25 | 144 | 6.1 |