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Target Snapshot

CHEMBL4483236 Target Snapshot

Farage · CELL-LINE · Homo sapiens

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25Compounds
16Assays
0Approved Drugs
24.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Farage as ChEMBL target CHEMBL4483236. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Farage
CELL-LINE · Homo sapiens
As of 2026-09-13
ChEMBL target ID
CHEMBL4483236
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Farage still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

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Need a meeting-ready explanation of why this target matters?
Evidence Card
Review-ready rationale with source-aware context

Open the one-page evidence card when you want the rationale, activity base, and attribution together.

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NameFarage
Target TypeCELL-LINE
OrganismHomo sapiens
ChEMBL ↗

Next Actions

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelFarage
UniProt AccessionN/A

Farage

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as Farage.

Review nameFarage
OrganismHomo sapiens
Clinical Profile

Clinical Phase Distribution

1
Phase I
Assay Mix

Activity Type Distribution

IC5022.0
EC502.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL67 9.15 IC50 0.7 Preclinical
CHEMBL1090479 8.15 EC50 7.0 Preclinical
CHEMBL5400566 7.75 IC50 17.6 Preclinical
CHEMBL4538610 6.0 IC50 1000.0 Preclinical
CHEMBL5204980 5.96 IC50 1100.0 Preclinical
CHEMBL4452230 5.15 IC50 7020.0 Preclinical
CHEMBL4451642 4.9 IC50 12640.0 Preclinical
CHEMBL4445279 4.87 IC50 13610.0 Preclinical
CHEMBL3578214 4.83 IC50 14940.0 Preclinical
CHEMBL4464645 4.8 IC50 15980.0 Preclinical
Distribution

pChEMBL Value Distribution

1
5.0
2
5.5
1
6.0
0
6.5
0
7.0
1
7.5
1
8.0
0
8.5
1
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

16
Total Assays
21
Tested Compounds
1
Assay Types
Functional — 16 assays, 21 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 16 21 5.3

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine