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Target Snapshot

CHEMBL4483258 Target Snapshot

MIN6 · CELL-LINE · Mus musculus

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67Compounds
31Assays
1Approved Drugs
26.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats MIN6 as ChEMBL target CHEMBL4483258. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
MIN6
CELL-LINE · Mus musculus
As of 2026-09-14
ChEMBL target ID
CHEMBL4483258
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether MIN6 still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

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Evidence Card
Review-ready rationale with source-aware context

Open the one-page evidence card when you want the rationale, activity base, and attribution together.

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NameMIN6
Target TypeCELL-LINE
OrganismMus musculus
ChEMBL ↗

Next Actions

SearchRun a focused querySearch the database using this target name as the starting context. ApprovalsCheck approved moleculesSee which approved drugs connect back to this target and its surrounding signal space. FeedScan papers & updatesStay in the project thread while checking recent papers and platform updates.
UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelMIN6
UniProt AccessionN/A

MIN6

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as MIN6.

Review nameMIN6
OrganismMus musculus
Clinical Profile

Clinical Phase Distribution

1
Approved
Assay Mix

Activity Type Distribution

EC5026.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL1829173 8.32 EC50 4.8 Preclinical
CHEMBL866 6.22 EC50 600.0 Approved
CHEMBL4089387 4.98 EC50 10400.0 Preclinical
CHEMBL4090188 4.96 EC50 11000.0 Preclinical
CHEMBL4070788 4.9 EC50 12700.0 Preclinical
CHEMBL4080536 4.85 EC50 14200.0 Preclinical
CHEMBL4100361 4.85 EC50 14200.0 Preclinical
CHEMBL4096956 4.73 EC50 18500.0 Preclinical
CHEMBL4097901 4.71 EC50 19300.0 Preclinical
CHEMBL4078940 4.68 EC50 21000.0 Preclinical
Distribution

pChEMBL Value Distribution

0
5.0
0
5.5
1
6.0
0
6.5
0
7.0
0
7.5
1
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Approved Drugs

Approved Drugs

MYCOPHENOLIC ACID
CHEMBL866
Approved 2004
Properties Compare Identifier
Assay Landscape

Assay Landscape

31
Total Assays
19
Tested Compounds
3
Assay Types
Functional — 24 assays, 19 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 24 19 4.7
ADME — 6 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 6 0 —
Toxicity — 1 assays, 2 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 1 2 5.4

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine