NRK-52E · CELL-LINE · Rattus norvegicus
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NRK-52E
Review this target as NRK-52E.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats NRK-52E as ChEMBL target CHEMBL4483282. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | NRK-52E |
| Target Type | CELL-LINE |
| Organism | Rattus norvegicus |
Reviewable protein naming and mapping context for this target snapshot.
Review this target as NRK-52E.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL486986 | 7.85 | EC50 | 14.2 | Preclinical |
| CHEMBL4467325 | 6.93 | EC50 | 117.5 | Preclinical |
| CHEMBL4648370 | 6.84 | EC50 | 145.7 | Preclinical |
| CHEMBL4643962 | 5.92 | EC50 | 1200.0 | Preclinical |
| CHEMBL5190933 | 5.9 | IC50 | 1250.0 | Preclinical |
| CHEMBL4643017 | 5.85 | EC50 | 1400.0 | Preclinical |
| CHEMBL4632544 | 5.8 | EC50 | 1600.0 | Preclinical |
| CHEMBL153 | 5.72 | EC50 | 1900.0 | Preclinical |
| CHEMBL4637927 | 4.94 | EC50 | 11500.0 | Preclinical |
| CHEMBL5426967 | 4.69 | IC50 | 20500.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 25 | 11 | 5.8 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 7 | 5 | 4.7 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 0 | — |