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Target Snapshot

CHEMBL4483283 Target Snapshot

Panc02 · CELL-LINE · Mus musculus

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86Compounds
73Assays
0Approved Drugs
49.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Panc02 as ChEMBL target CHEMBL4483283. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Panc02
CELL-LINE · Mus musculus
As of 2026-09-14
ChEMBL target ID
CHEMBL4483283
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Panc02 still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

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Need a meeting-ready explanation of why this target matters?
Evidence Card
Review-ready rationale with source-aware context

Open the one-page evidence card when you want the rationale, activity base, and attribution together.

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NamePanc02
Target TypeCELL-LINE
OrganismMus musculus
ChEMBL ↗

Next Actions

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelPanc02
UniProt AccessionN/A

Panc02

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as Panc02.

Review namePanc02
OrganismMus musculus
Clinical Profile

Clinical Phase Distribution

1
Phase II
Assay Mix

Activity Type Distribution

IC5039.0
EC5010.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL5401853 7.92 IC50 12.0 Preclinical
CHEMBL5403434 7.72 IC50 19.0 Preclinical
CHEMBL221190 7.21 IC50 61.0 Preclinical
CHEMBL5436752 6.67 IC50 216.0 Preclinical
CHEMBL5420878 6.58 IC50 261.0 Preclinical
CHEMBL5425511 6.57 IC50 270.0 Preclinical
CHEMBL2097911 6.52 IC50 300.0 Preclinical
CHEMBL3919996 6.23 EC50 590.0 Preclinical
CHEMBL4285825 5.93 EC50 1170.0 Preclinical
CHEMBL4277892 5.92 EC50 1210.0 Preclinical
Distribution

pChEMBL Value Distribution

2
5.0
7
5.5
1
6.0
4
6.5
1
7.0
2
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

73
Total Assays
22
Tested Compounds
2
Assay Types
Functional — 71 assays, 22 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 47 2 4.8
cell-based format 24 20 6.0
ADME — 2 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 2 0 —

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine