Use lice infestation as the disease frame, then confirm a stable protein accession before cross-source reuse.
CHEMBL4495552 Target Snapshot
Metalloproteinase · UNKNOWN · Pediculus humanus capitis
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As of 2026-09-14Metalloproteinase shows approved-linked disease relevance led by lice infestation. 1 more disease program remain visible in the same review block. 1 linked drug keeps the current disease frame grounded. Use lice infestation as the disease frame, then confirm a stable protein accession before cross-source reuse.
Metalloproteinase shows approved-linked disease relevance led by lice infestation. 1 more disease program remain visible in the same review block. 1 linked drug remains visible in the same block.
Start review with lice infestation because it currently carries approved-linked support. Linked drugs include ABAMETAPIR. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.
Disease source · ChEMBL drug mechanism + indication proxyMetalloproteinase
Review this target as Metalloproteinase.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Metalloproteinase as ChEMBL target CHEMBL4495552. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
Start with the right source
Choose the first block or source based on the question you are trying to answer.
Start here when your first question is whether Metalloproteinase still has a stable protein naming contract across sources.
Jump to Protein ContextUse this block first when you need to confirm why lice infestation is currently framed as approved-linked support. It currently carries 1 linked drug in the same disease frame.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
Open Review-ready CardBasic Information
Verify identity, organism, and the fastest next research jumps from the same page.
| Preferred Name | Metalloproteinase |
| Target Type | UNKNOWN |
| Organism | Pediculus humanus capitis |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
How to read this target
Review this target as Metalloproteinase.
Disease Relevance & Evidence Level
Open Targets-ready disease context using the current target-indication evidence contract.
Metalloproteinase shows approved-linked disease relevance led by lice infestation. 1 more disease program remain visible in the same review block.
How to read disease relevance
Start review with lice infestation because it currently carries approved-linked support. Linked drugs include ABAMETAPIR. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.