Glutaminyl-peptide cyclotransferase · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q16769. Use UniProt Q16769 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q16769 as the stable identity anchor, then attach disease evidence before program review.
Glutaminyl-peptide cyclotransferase
Review this target as Glutaminyl-peptide cyclotransferase, mapped to UniProt Q16769. Sequence length is 361 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Glutaminyl-peptide cyclotransferase as ChEMBL target CHEMBL4508, mapped to UniProt Q16769. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Glutaminyl-peptide cyclotransferase |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q16769 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Glutaminyl-peptide cyclotransferase |
| UniProt Accession | Q16769 |
| Component Type | Protein |
| Sequence Length | 361 aa |
Glutaminyl-peptide cyclotransferase
Review this target as Glutaminyl-peptide cyclotransferase, mapped to UniProt Q16769. Sequence length is 361 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4462495 | 10.28 | IC50 | 0.053 | Preclinical |
| CHEMBL5092802 | 10.0 | IC50 | 0.1 | Preclinical |
| CHEMBL5085353 | 9.52 | IC50 | 0.3 | Preclinical |
| CHEMBL5086776 | 9.34 | IC50 | 0.46 | Preclinical |
| CHEMBL5085226 | 9.3 | IC50 | 0.5 | Preclinical |
| CHEMBL5075575 | 9.22 | IC50 | 0.6 | Preclinical |
| CHEMBL4077433 | 9.15 | IC50 | 0.7 | Preclinical |
| CHEMBL5089771 | 9.15 | IC50 | 0.71 | Preclinical |
| CHEMBL5083519 | 9.1 | IC50 | 0.8 | Preclinical |
| CHEMBL5085670 | 9.0 | IC50 | 1.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 29 | 702 | 6.8 |
| assay format | 8 | 169 | 6.0 |
| cell-based format | 7 | 102 | 7.3 |