Cysteine protease falcipain-3 · SINGLE PROTEIN · Plasmodium falciparum
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As of 2026-09-14Protein identity stays anchored to UniProt Q9NBA7. Use UniProt Q9NBA7 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9NBA7 as the stable identity anchor, then attach disease evidence before program review.
Cysteine protease falcipain-3
Review this target as Cysteine protease falcipain-3, mapped to UniProt Q9NBA7. Sequence length is 488 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Cysteine protease falcipain-3 as ChEMBL target CHEMBL4510, mapped to UniProt Q9NBA7. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Cysteine protease falcipain-3 |
| Target Type | SINGLE PROTEIN |
| Organism | Plasmodium falciparum |
| UniProt | Q9NBA7 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Cysteine protease falcipain-3 |
| UniProt Accession | Q9NBA7 |
| Component Type | Protein |
| Sequence Length | 488 aa |
Cysteine protease falcipain-3
Review this target as Cysteine protease falcipain-3, mapped to UniProt Q9NBA7. Sequence length is 488 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL486232 | 7.68 | IC50 | 21.0 | Preclinical |
| CHEMBL374508 | 7.46 | IC50 | 35.0 | Preclinical |
| CHEMBL224801 | 5.31 | IC50 | 4900.0 | Preclinical |
| CHEMBL221833 | 5.27 | IC50 | 5400.0 | Preclinical |
| CHEMBL224803 | 5.27 | IC50 | 5400.0 | Preclinical |
| CHEMBL222325 | 5.24 | IC50 | 5800.0 | Preclinical |
| CHEMBL222870 | 5.12 | IC50 | 7500.0 | Preclinical |
| CHEMBL438659 | 4.98 | IC50 | 10500.0 | Preclinical |
| CHEMBL381093 | 4.94 | IC50 | 11400.0 | Preclinical |
| CHEMBL221991 | 4.93 | IC50 | 11800.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 3 | 22 | 5.1 |