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Target Snapshot

CHEMBL4513193 Target Snapshot

Western equine encephalitis virus · ORGANISM · Western equine encephalitis virus

28Compounds
4Assays
0Approved Drugs
28.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

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Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Western equine encephalitis virus as ChEMBL target CHEMBL4513193. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Western equine encephalitis virus
ORGANISM · Western equine encephalitis virus
As of 2026-09-14
ChEMBL target ID
CHEMBL4513193
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Western equine encephalitis virus still has a stable protein naming contract across sources.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelWestern equine encephalitis virus
UniProt AccessionN/A

Western equine encephalitis virus

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Western equine encephalitis virus.

Review nameWestern equine encephalitis virus
OrganismWestern equine encephalitis virus
Clinical Profile

Clinical Phase Distribution

1
Phase II
Assay Mix

Activity Type Distribution

IC5026.0
EC502.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL4562509 8.62 EC50 2.4 Preclinical
CHEMBL5283742 8.52 IC50 3.0 Preclinical
CHEMBL38434 7.11 EC50 78.0 Clinical
CHEMBL4863446 6.31 IC50 490.0 Preclinical
CHEMBL4870800 6.28 IC50 530.0 Preclinical
CHEMBL4861900 6.02 IC50 960.0 Preclinical
CHEMBL4849010 5.77 IC50 1700.0 Preclinical
CHEMBL4856254 5.41 IC50 3900.0 Preclinical
CHEMBL4857635 5.15 IC50 7100.0 Preclinical
CHEMBL4862885 4.96 IC50 10900.0 Preclinical
Distribution

pChEMBL Value Distribution

2
5.0
1
5.5
3
6.0
0
6.5
1
7.0
0
7.5
0
8.0
2
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

4
Total Assays
17
Tested Compounds
1
Assay Types
Functional — 4 assays, 17 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 4 17 5.7

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine