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Target Snapshot

CHEMBL4523072 Target Snapshot

Junin virus · ORGANISM · Mammarenavirus juninense

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140Compounds
31Assays
4Approved Drugs
159.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Junin virus as ChEMBL target CHEMBL4523072. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Junin virus
ORGANISM · Mammarenavirus juninense
As of 2026-09-13
ChEMBL target ID
CHEMBL4523072
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

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Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Junin virus still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NameJunin virus
Target TypeORGANISM
OrganismMammarenavirus juninense
ChEMBL ↗ NCBI Taxonomy ↗

Next Actions

SearchRun a focused querySearch the database using this target name as the starting context. ApprovalsCheck approved moleculesSee which approved drugs connect back to this target and its surrounding signal space. FeedScan papers & updatesStay in the project thread while checking recent papers and platform updates.
UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelJunin virus
UniProt AccessionN/A

Junin virus

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as Junin virus.

Review nameJunin virus
OrganismMammarenavirus juninense
Clinical Profile

Clinical Phase Distribution

4
Approved
Assay Mix

Activity Type Distribution

IC5010.0
EC50149.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL4856859 10.22 EC50 0.06 Preclinical
CHEMBL4871373 9.96 EC50 0.11 Preclinical
CHEMBL4853992 9.92 EC50 0.12 Preclinical
CHEMBL4860136 9.92 EC50 0.12 Preclinical
CHEMBL4852706 9.8 EC50 0.16 Preclinical
CHEMBL4858248 9.8 EC50 0.16 Preclinical
CHEMBL4851799 9.77 EC50 0.17 Preclinical
CHEMBL4871905 9.72 EC50 0.19 Preclinical
CHEMBL3961047 9.7 IC50 0.2 Preclinical
CHEMBL4853959 9.68 EC50 0.21 Preclinical
Distribution

pChEMBL Value Distribution

6
5.0
6
5.5
6
6.0
5
6.5
2
7.0
9
7.5
15
8.0
11
8.5
16
9.0
14
9.5
pChEMBL
Approved Drugs

Approved Drugs

REMDESIVIR
CHEMBL4065616
Approved 2020
Properties Compare Identifier
Assay Landscape

Assay Landscape

31
Total Assays
103
Tested Compounds
1
Assay Types
Functional — 31 assays, 103 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 30 102 7.4
assay format 1 1 9.7

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine