Glutaminase kidney isoform, mitochondrial · SINGLE PROTEIN · Mus musculus
This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.
Move to another high-traffic target or paste a specific ChEMBL target ID.
Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt D3Z7P3. Use UniProt D3Z7P3 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt D3Z7P3 as the stable identity anchor, then attach disease evidence before program review.
Glutaminase kidney isoform, mitochondrial
Review this target as Glutaminase kidney isoform, mitochondrial, mapped to UniProt D3Z7P3. Sequence length is 674 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Glutaminase kidney isoform, mitochondrial as ChEMBL target CHEMBL4523110, mapped to UniProt D3Z7P3. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
Choose the first block or source based on the question you are trying to answer.
Start here when your first question is whether Glutaminase kidney isoform, mitochondrial is the right protein anchor across sources, using UniProt D3Z7P3 as the stable mapping.
Jump to Protein ContextUse this block first when you need the strongest disease program and evidence level in one place.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
Open Review-ready CardVerify identity, organism, and the fastest next research jumps from the same page.
| Preferred Name | Glutaminase kidney isoform, mitochondrial |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | D3Z7P3 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Glutaminase kidney isoform, mitochondrial |
| UniProt Accession | D3Z7P3 |
| Component Type | Protein |
| Sequence Length | 674 aa |
Glutaminase kidney isoform, mitochondrial
Review this target as Glutaminase kidney isoform, mitochondrial, mapped to UniProt D3Z7P3. Sequence length is 674 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3639788 | 7.7 | IC50 | 20.0 | Clinical |
| CHEMBL4462220 | 7.3 | IC50 | 50.0 | Preclinical |
| CHEMBL4562029 | 7.3 | IC50 | 50.0 | Preclinical |
| CHEMBL4537860 | 6.0 | IC50 | 1000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| organism-based format | 12 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| tissue-based format | 5 | 1 | 7.7 |
| single protein format | 4 | 3 | 6.9 |