Use UniProt P46091 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL4523229 Target Snapshot
Chemerin-like receptor 2 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P46091. Use UniProt P46091 as the stable identity anchor, then attach disease evidence before program review.
Chemerin-like receptor 2
Review this target as Chemerin-like receptor 2, mapped to UniProt P46091. Sequence length is 355 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Chemerin-like receptor 2 as ChEMBL target CHEMBL4523229, mapped to UniProt P46091. Disease framing currently uses the Open Targets-ready proxy contract.
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Open Review-ready CardBasic Information
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| Preferred Name | Chemerin-like receptor 2 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P46091 |
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UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Chemerin-like receptor 2 |
| UniProt Accession | P46091 |
| Component Type | Protein |
| Sequence Length | 355 aa |
Chemerin-like receptor 2
How to read this target
Review this target as Chemerin-like receptor 2, mapped to UniProt P46091. Sequence length is 355 aa.
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5315640 | 7.8 | EC50 | 15.85 | Preclinical |
| CHEMBL5081975 | 7.45 | Ki | 35.4 | Preclinical |
| CHEMBL4470851 | 7.34 | EC50 | 46.1 | Preclinical |
| CHEMBL4517021 | 7.25 | EC50 | 55.6 | Preclinical |
| CHEMBL4447799 | 7.21 | EC50 | 60.9 | Preclinical |
| CHEMBL4568879 | 7.03 | EC50 | 92.8 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Functional — 7 assays, 1 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 7 | 1 | 6.9 |
Binding — 5 assays, 5 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 3 | 5 | 7.3 |
| single protein format | 2 | 0 | — |