Prolyl 4-hydroxylase · SINGLE PROTEIN · Paramecium bursaria Chlorella virus 1
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As of 2026-09-13Protein identity stays anchored to UniProt Q84406. Use UniProt Q84406 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q84406 as the stable identity anchor, then attach disease evidence before program review.
Prolyl 4-hydroxylase
Review this target as Prolyl 4-hydroxylase, mapped to UniProt Q84406. Sequence length is 242 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Prolyl 4-hydroxylase as ChEMBL target CHEMBL4523368, mapped to UniProt Q84406. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Prolyl 4-hydroxylase is the right protein anchor across sources, using UniProt Q84406 as the stable mapping.
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| Preferred Name | Prolyl 4-hydroxylase |
| Target Type | SINGLE PROTEIN |
| Organism | Paramecium bursaria Chlorella virus 1 |
| UniProt | Q84406 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Prolyl 4-hydroxylase |
| UniProt Accession | Q84406 |
| Component Type | Protein |
| Sequence Length | 242 aa |
Prolyl 4-hydroxylase
Review this target as Prolyl 4-hydroxylase, mapped to UniProt Q84406. Sequence length is 242 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3646221 | 6.55 | Ki | 280.0 | Approved |
| CHEMBL426560 | 6.15 | Ki | 710.0 | Preclinical |
| CHEMBL2338329 | 5.97 | Ki | 1070.0 | Approved |
| CHEMBL3646117 | 5.6 | IC50 | 2500.0 | Preclinical |
| CHEMBL316034 | 5.48 | Ki | 3280.0 | Preclinical |
| CHEMBL426560 | 5.35 | IC50 | 4500.0 | Preclinical |
| CHEMBL2338329 | 5.3 | IC50 | 5000.0 | Approved |
| CHEMBL316034 | 5.28 | IC50 | 5300.0 | Preclinical |
| CHEMBL4163812 | 5.12 | Ki | 7650.0 | Preclinical |
| CHEMBL3186774 | 5.07 | IC50 | 8500.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 13 | 14 | 5.2 |