Use UniProt Q8CIM5 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL4523386 Target Snapshot
G-protein coupled receptor 84 · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt Q8CIM5. Use UniProt Q8CIM5 as the stable identity anchor, then attach disease evidence before program review.
G-protein coupled receptor 84
Review this target as G-protein coupled receptor 84, mapped to UniProt Q8CIM5. Sequence length is 396 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats G-protein coupled receptor 84 as ChEMBL target CHEMBL4523386, mapped to UniProt Q8CIM5. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | G-protein coupled receptor 84 |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | Q8CIM5 |
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UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | G-protein coupled receptor 84 |
| UniProt Accession | Q8CIM5 |
| Component Type | Protein |
| Sequence Length | 396 aa |
G-protein coupled receptor 84
How to read this target
Review this target as G-protein coupled receptor 84, mapped to UniProt Q8CIM5. Sequence length is 396 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3827756 | 7.89 | EC50 | 12.9 | Preclinical |
| CHEMBL3716446 | 7.41 | IC50 | 39.0 | Preclinical |
| CHEMBL3715656 | 7.17 | IC50 | 68.0 | Preclinical |
| CHEMBL4088884 | 6.75 | EC50 | 178.0 | Preclinical |
| CHEMBL5179395 | 6.56 | IC50 | 273.0 | Preclinical |
| CHEMBL5194984 | 6.34 | IC50 | 454.0 | Preclinical |
| CHEMBL4776061 | 6.2 | IC50 | 636.0 | Preclinical |
| CHEMBL446452 | 5.37 | EC50 | 4270.0 | Clinical |
pChEMBL Value Distribution
Assay Landscape
Functional — 16 assays, 10 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 9 | 4 | 6.6 |
| cell membrane format | 6 | 4 | 6.8 |
| tissue-based format | 1 | 2 | 6.7 |
Binding — 1 assays, 0 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell membrane format | 1 | 0 | — |