Kinesin-like protein KIF18A · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q8NI77. Use UniProt Q8NI77 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q8NI77 as the stable identity anchor, then attach disease evidence before program review.
Kinesin-like protein KIF18A
Review this target as Kinesin-like protein KIF18A, mapped to UniProt Q8NI77. Sequence length is 898 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Kinesin-like protein KIF18A as ChEMBL target CHEMBL4523403, mapped to UniProt Q8NI77. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Kinesin-like protein KIF18A is the right protein anchor across sources, using UniProt Q8NI77 as the stable mapping.
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| Preferred Name | Kinesin-like protein KIF18A |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q8NI77 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Kinesin-like protein KIF18A |
| UniProt Accession | Q8NI77 |
| Component Type | Protein |
| Sequence Length | 898 aa |
Kinesin-like protein KIF18A
Review this target as Kinesin-like protein KIF18A, mapped to UniProt Q8NI77. Sequence length is 898 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4755023 | 7.92 | IC50 | 12.0 | Preclinical |
| CHEMBL4776977 | 7.92 | IC50 | 12.0 | Preclinical |
| CHEMBL4784192 | 7.92 | IC50 | 12.0 | Preclinical |
| CHEMBL5070813 | 7.89 | IC50 | 13.0 | Preclinical |
| CHEMBL4752657 | 7.85 | IC50 | 14.0 | Preclinical |
| CHEMBL4777623 | 7.85 | IC50 | 14.0 | Preclinical |
| CHEMBL5075318 | 7.82 | IC50 | 15.0 | Preclinical |
| CHEMBL4746340 | 7.8 | IC50 | 16.0 | Preclinical |
| CHEMBL4777759 | 7.8 | IC50 | 16.0 | Preclinical |
| CHEMBL5081181 | 7.8 | IC50 | 16.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 11 | 841 | 7.0 |
| single protein format | 4 | 198 | 7.0 |
| cell-based format | 1 | 26 | 6.4 |