Use UniProt Q9D4B1 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL4523444 Target Snapshot
Phosphatidylcholine:ceramide cholinephosphotransferase 2 · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt Q9D4B1. Use UniProt Q9D4B1 as the stable identity anchor, then attach disease evidence before program review.
Phosphatidylcholine:ceramide cholinephosphotransferase 2
Review this target as Phosphatidylcholine:ceramide cholinephosphotransferase 2, mapped to UniProt Q9D4B1. Sequence length is 365 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Phosphatidylcholine:ceramide cholinephosphotransferase 2 as ChEMBL target CHEMBL4523444, mapped to UniProt Q9D4B1. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Phosphatidylcholine:ceramide cholinephosphotransferase 2 |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | Q9D4B1 |
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UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Phosphatidylcholine:ceramide cholinephosphotransferase 2 |
| UniProt Accession | Q9D4B1 |
| Component Type | Protein |
| Sequence Length | 365 aa |
Phosphatidylcholine:ceramide cholinephosphotransferase 2
How to read this target
Review this target as Phosphatidylcholine:ceramide cholinephosphotransferase 2, mapped to UniProt Q9D4B1. Sequence length is 365 aa.
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4645607 | 8.66 | IC50 | 2.2 | Preclinical |
| CHEMBL4641888 | 8.52 | IC50 | 3.0 | Preclinical |
| CHEMBL4646354 | 8.11 | IC50 | 7.7 | Preclinical |
| CHEMBL4644293 | 7.85 | IC50 | 14.0 | Preclinical |
| CHEMBL4638337 | 7.72 | IC50 | 19.0 | Preclinical |
| CHEMBL4646540 | 7.5 | IC50 | 32.0 | Preclinical |
| CHEMBL4639746 | 7.29 | IC50 | 51.0 | Preclinical |
| CHEMBL4634697 | 6.92 | IC50 | 120.0 | Preclinical |
| CHEMBL4638097 | 6.72 | IC50 | 190.0 | Preclinical |
| CHEMBL4634669 | 6.62 | IC50 | 240.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 5 assays, 16 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 2 | 0 | — |
| assay format | 1 | 15 | 7.2 |
| cell-based format | 1 | 1 | 5.0 |
| subcellular format | 1 | 0 | — |