Use UniProt Q9D8T2 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL4523446 Target Snapshot
Gasdermin-D · SINGLE PROTEIN · Mus musculus
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As of 2026-09-13Protein identity stays anchored to UniProt Q9D8T2. Use UniProt Q9D8T2 as the stable identity anchor, then attach disease evidence before program review.
Gasdermin-D
Review this target as Gasdermin-D, mapped to UniProt Q9D8T2. Sequence length is 487 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Gasdermin-D as ChEMBL target CHEMBL4523446, mapped to UniProt Q9D8T2. Disease framing currently uses the Open Targets-ready proxy contract.
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Open Review-ready CardBasic Information
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| Preferred Name | Gasdermin-D |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | Q9D8T2 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Gasdermin-D |
| UniProt Accession | Q9D8T2 |
| Component Type | Protein |
| Sequence Length | 487 aa |
Gasdermin-D
How to read this target
Review this target as Gasdermin-D, mapped to UniProt Q9D8T2. Sequence length is 487 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
pChEMBL Value Distribution
Approved Drugs
Assay Landscape
Binding — 5 assays, 2 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 2 | 0 | — |
| single protein format | 2 | 2 | 6.4 |
| assay format | 1 | 0 | — |