Programmed cell death 1 ligand 1 · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt Q9EP73. Use UniProt Q9EP73 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9EP73 as the stable identity anchor, then attach disease evidence before program review.
Programmed cell death 1 ligand 1
Review this target as Programmed cell death 1 ligand 1, mapped to UniProt Q9EP73. Sequence length is 290 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Programmed cell death 1 ligand 1 as ChEMBL target CHEMBL4523448, mapped to UniProt Q9EP73. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Programmed cell death 1 ligand 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | Q9EP73 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Programmed cell death 1 ligand 1 |
| UniProt Accession | Q9EP73 |
| Component Type | Protein |
| Sequence Length | 290 aa |
Programmed cell death 1 ligand 1
Review this target as Programmed cell death 1 ligand 1, mapped to UniProt Q9EP73. Sequence length is 290 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5271329 | 7.57 | EC50 | 27.0 | Preclinical |
| CHEMBL4438020 | 7.52 | EC50 | 30.0 | Preclinical |
| CHEMBL5287840 | 7.52 | EC50 | 30.0 | Preclinical |
| CHEMBL5562590 | 7.5 | Kd | 31.8 | Preclinical |
| CHEMBL5197008 | 7.47 | EC50 | 33.79 | Preclinical |
| CHEMBL5289147 | 7.4 | EC50 | 40.0 | Preclinical |
| CHEMBL4748886 | 7.33 | Kd | 47.0 | Preclinical |
| CHEMBL5400320 | 7.14 | Kd | 73.1 | Preclinical |
| CHEMBL5403275 | 6.66 | Kd | 217.7 | Preclinical |
| CHEMBL5532039 | 6.43 | Kd | 368.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 17 | 11 | 6.7 |
| single protein format | 12 | 6 | 6.4 |
| tissue-based format | 2 | 0 | — |
| assay format | 1 | 0 | — |