C5a anaphylatoxin chemotactic receptor 2 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q9P296. Use UniProt Q9P296 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9P296 as the stable identity anchor, then attach disease evidence before program review.
C5a anaphylatoxin chemotactic receptor 2
Review this target as C5a anaphylatoxin chemotactic receptor 2, mapped to UniProt Q9P296. Sequence length is 337 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats C5a anaphylatoxin chemotactic receptor 2 as ChEMBL target CHEMBL4523478, mapped to UniProt Q9P296. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | C5a anaphylatoxin chemotactic receptor 2 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9P296 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | C5a anaphylatoxin chemotactic receptor 2 |
| UniProt Accession | Q9P296 |
| Component Type | Protein |
| Sequence Length | 337 aa |
C5a anaphylatoxin chemotactic receptor 2
Review this target as C5a anaphylatoxin chemotactic receptor 2, mapped to UniProt Q9P296. Sequence length is 337 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5594087 | 6.69 | Kd | 203.0 | Preclinical |
| CHEMBL5594178 | 6.69 | Kd | 203.0 | Preclinical |
| CHEMBL1707 | 5.9 | EC50 | 1251.33 | Approved |
| CHEMBL4518532 | 5.23 | EC50 | 5900.0 | Preclinical |
| CHEMBL4550325 | 5.12 | EC50 | 7600.0 | Preclinical |
| CHEMBL4550325 | 4.32 | Ki | 48000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 11 | 2 | 6.6 |
| cell-based format | 4 | 2 | 4.9 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 1 | 5.9 |