Use UniProt Q9UKJ3 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL4523489 Target Snapshot
G patch domain-containing protein 8 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q9UKJ3. Use UniProt Q9UKJ3 as the stable identity anchor, then attach disease evidence before program review.
G patch domain-containing protein 8
Review this target as G patch domain-containing protein 8, mapped to UniProt Q9UKJ3. Sequence length is 1502 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats G patch domain-containing protein 8 as ChEMBL target CHEMBL4523489, mapped to UniProt Q9UKJ3. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether G patch domain-containing protein 8 is the right protein anchor across sources, using UniProt Q9UKJ3 as the stable mapping.
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Open Review-ready CardBasic Information
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| Preferred Name | G patch domain-containing protein 8 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9UKJ3 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | G patch domain-containing protein 8 |
| UniProt Accession | Q9UKJ3 |
| Component Type | Protein |
| Sequence Length | 1502 aa |
G patch domain-containing protein 8
How to read this target
Review this target as G patch domain-containing protein 8, mapped to UniProt Q9UKJ3. Sequence length is 1502 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1232461 | 8.0 | IC50 | 10.0 | Clinical |
| CHEMBL1232461 | 7.92 | Kd | 12.0 | Clinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 8 assays, 1 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 7 | 1 | 8.0 |
| subcellular format | 1 | 0 | — |