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Target Snapshot

CHEMBL4523561 Target Snapshot

SU-DHL-5 · CELL-LINE · Homo sapiens

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29Compounds
12Assays
0Approved Drugs
11.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats SU-DHL-5 as ChEMBL target CHEMBL4523561. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
SU-DHL-5
CELL-LINE · Homo sapiens
As of 2026-09-14
ChEMBL target ID
CHEMBL4523561
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether SU-DHL-5 still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Jump to Disease Context
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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NameSU-DHL-5
Target TypeCELL-LINE
OrganismHomo sapiens
ChEMBL ↗

Next Actions

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelSU-DHL-5
UniProt AccessionN/A

SU-DHL-5

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as SU-DHL-5.

Review nameSU-DHL-5
OrganismHomo sapiens
Clinical Profile

Clinical Phase Distribution

1
Phase I
Assay Mix

Activity Type Distribution

IC508.0
EC503.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL3629671 9.0 IC50 1.0 Preclinical
CHEMBL4462577 8.44 IC50 3.6 Preclinical
CHEMBL1090479 8.3 EC50 5.0 Preclinical
CHEMBL5612001 7.28 IC50 52.0 Preclinical
CHEMBL5613531 6.75 IC50 176.0 Preclinical
CHEMBL4282264 6.12 EC50 760.0 Preclinical
CHEMBL5613124 5.71 IC50 1950.0 Preclinical
CHEMBL5268484 5.3 IC50 5000.0 Preclinical
CHEMBL5196874 5.05 EC50 9000.0 Preclinical
CHEMBL5282240 4.99 IC50 10290.0 Preclinical
Distribution

pChEMBL Value Distribution

2
5.0
1
5.5
1
6.0
1
6.5
1
7.0
0
7.5
2
8.0
0
8.5
1
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

12
Total Assays
11
Tested Compounds
1
Assay Types
Functional — 12 assays, 11 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 12 11 6.5

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine