Protein cereblon/Estrogen receptor · PROTEIN-PROTEIN INTERACTION · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P03372. Use UniProt P03372 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P03372 as the stable identity anchor, then attach disease evidence before program review.
Estrogen receptor
Review this target as Protein cereblon/Estrogen receptor, mapped to UniProt P03372. ChEMBL maps the protein component as Estrogen receptor. Sequence length is 595 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Protein cereblon/Estrogen receptor as ChEMBL target CHEMBL4523681, mapped to UniProt P03372. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Protein cereblon/Estrogen receptor |
| Target Type | PROTEIN-PROTEIN INTERACTION |
| Organism | Homo sapiens |
| UniProt | P03372 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Estrogen receptor |
| UniProt Accession | P03372 |
| Component Type | Protein |
| Sequence Length | 595 aa |
Estrogen receptor
Review this target as Protein cereblon/Estrogen receptor, mapped to UniProt P03372. ChEMBL maps the protein component as Estrogen receptor. Sequence length is 595 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4745409 | 9.4 | IC50 | 0.4 | Preclinical |
| CHEMBL4745755 | 9.4 | IC50 | 0.4 | Preclinical |
| CHEMBL4754618 | 9.4 | IC50 | 0.4 | Preclinical |
| CHEMBL4760508 | 9.4 | IC50 | 0.4 | Preclinical |
| CHEMBL4800591 | 9.4 | IC50 | 0.4 | Preclinical |
| CHEMBL4781967 | 9.3 | IC50 | 0.5 | Preclinical |
| CHEMBL4785047 | 9.3 | IC50 | 0.5 | Preclinical |
| CHEMBL4792381 | 9.3 | IC50 | 0.5 | Preclinical |
| CHEMBL4747484 | 9.22 | IC50 | 0.6 | Preclinical |
| CHEMBL4791102 | 9.22 | IC50 | 0.6 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 30 | 16 | 9.0 |
| tissue-based format | 1 | 0 | — |