G-protein coupled receptor 3 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P46089. Use UniProt P46089 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P46089 as the stable identity anchor, then attach disease evidence before program review.
G-protein coupled receptor 3
Review this target as G-protein coupled receptor 3, mapped to UniProt P46089. Sequence length is 330 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats G-protein coupled receptor 3 as ChEMBL target CHEMBL4523856, mapped to UniProt P46089. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | G-protein coupled receptor 3 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P46089 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | G-protein coupled receptor 3 |
| UniProt Accession | P46089 |
| Component Type | Protein |
| Sequence Length | 330 aa |
G-protein coupled receptor 3
Review this target as G-protein coupled receptor 3, mapped to UniProt P46089. Sequence length is 330 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5410506 | 6.99 | Kd | 102.33 | Preclinical |
| CHEMBL5415054 | 6.86 | EC50 | 137.0 | Preclinical |
| CHEMBL5425788 | 6.64 | EC50 | 230.0 | Preclinical |
| CHEMBL5399736 | 6.58 | EC50 | 260.0 | Preclinical |
| CHEMBL5432166 | 6.56 | EC50 | 277.0 | Preclinical |
| CHEMBL5410506 | 6.53 | Ki | 295.12 | Preclinical |
| CHEMBL5409202 | 6.34 | EC50 | 455.0 | Preclinical |
| CHEMBL5427433 | 6.09 | EC50 | 816.0 | Preclinical |
| CHEMBL5410506 | 6.05 | EC50 | 891.25 | Preclinical |
| CHEMBL4302437 | 6.04 | EC50 | 921.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 14 | 5 | 5.9 |
| single protein format | 2 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 8 | 35 | 5.4 |