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Target Snapshot

CHEMBL4523925 Target Snapshot

G-protein coupled receptor family C group 5 member D · SINGLE PROTEIN · Homo sapiens

2Compounds
2Assays
0Approved Drugs
0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

G-protein coupled receptor family C group 5 member D shows approved-linked disease relevance led by multiple myeloma. 2 more disease programs remain visible in the same review block. 1 linked drug keeps the current disease frame grounded. Protein identity stays anchored to UniProt Q9NZD1. Start with multiple myeloma, then reuse UniProt Q9NZD1 as the stable protein anchor across project notes and exports.

Review focus
Review-ready target frame

Start with multiple myeloma, then reuse UniProt Q9NZD1 as the stable protein anchor across project notes and exports.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13 1 linked drug
Open source guide
Disease program
multiple myeloma

G-protein coupled receptor family C group 5 member D shows approved-linked disease relevance led by multiple myeloma. 2 more disease programs remain visible in the same review block. 1 linked drug remains visible in the same block.

Start review with multiple myeloma because it currently carries approved-linked support. Linked drugs include TALQUETAMAB. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.

Disease source · ChEMBL drug mechanism + indication proxy
Approved-linked Open Targets-ready proxy 1 linked drug
Open disease block
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats G-protein coupled receptor family C group 5 member D as ChEMBL target CHEMBL4523925, mapped to UniProt Q9NZD1. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
G-protein coupled receptor family C group 5 member D
SINGLE PROTEIN · Homo sapiens
As of 2026-09-13
ChEMBL target ID
CHEMBL4523925
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
UniProt accession
Q9NZD1
G-protein coupled receptor family C group 5 member D
UniProt accession via ChEMBL component mapping As of 2026-09-13
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether G-protein coupled receptor family C group 5 member D is the right protein anchor across sources, using UniProt Q9NZD1 as the stable mapping.

Jump to Protein Context
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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need to confirm why multiple myeloma is currently framed as approved-linked support. It currently carries 1 linked drug in the same disease frame.

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelG-protein coupled receptor family C group 5 member D
UniProt AccessionQ9NZD1
Component TypeProtein
Sequence Length345 aa

G-protein coupled receptor family C group 5 member D

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as G-protein coupled receptor family C group 5 member D, mapped to UniProt Q9NZD1. Sequence length is 345 aa.

Mapped IDQ9NZD1
Review nameG-protein coupled receptor family C group 5 member D
OrganismHomo sapiens
Disease Relevance

Disease Relevance & Evidence Level

Open Targets-ready disease context using the current target-indication evidence contract.

Approved-linked Open Targets-ready proxy

G-protein coupled receptor family C group 5 member D shows approved-linked disease relevance led by multiple myeloma. 2 more disease programs remain visible in the same review block.

Approved-linked Approved
multiple myeloma
1 linked drug · 1 direct · 1 efficacy
Linked drugTALQUETAMAB
Approved-linked Approved
neoplasm
1 linked drug · 1 direct · 1 efficacy
Linked drugTALQUETAMAB
Clinical signal Phase II
hematologic disorder
1 linked drug · 1 direct · 1 efficacy
Linked drugTALQUETAMAB
Source · ChEMBL drug mechanism + indication proxy
Review Cue

How to read disease relevance

Start review with multiple myeloma because it currently carries approved-linked support. Linked drugs include TALQUETAMAB. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.

Lead diseasemultiple myeloma
Strongest levelApproved-linked
Block modeOpen Targets-ready proxy
Distribution

pChEMBL Value Distribution

0
5.0
0
5.5
0
6.0
0
6.5
0
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

2
Total Assays
0
Tested Compounds
1
Assay Types
Binding — 2 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
single protein format 2 0

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine