tRNA (guanine-N(1)-)-methyltransferase · SINGLE PROTEIN · Staphylococcus aureus (strain NCTC 8325 / PS 47)
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As of 2026-09-14Protein identity stays anchored to UniProt Q2FZ43. Use UniProt Q2FZ43 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q2FZ43 as the stable identity anchor, then attach disease evidence before program review.
tRNA (guanine-N(1)-)-methyltransferase
Review this target as tRNA (guanine-N(1)-)-methyltransferase, mapped to UniProt Q2FZ43. Sequence length is 245 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats tRNA (guanine-N(1)-)-methyltransferase as ChEMBL target CHEMBL4523934, mapped to UniProt Q2FZ43. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether tRNA (guanine-N(1)-)-methyltransferase is the right protein anchor across sources, using UniProt Q2FZ43 as the stable mapping.
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| Preferred Name | tRNA (guanine-N(1)-)-methyltransferase |
| Target Type | SINGLE PROTEIN |
| Organism | Staphylococcus aureus (strain NCTC 8325 / PS 47) |
| UniProt | Q2FZ43 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | tRNA (guanine-N(1)-)-methyltransferase |
| UniProt Accession | Q2FZ43 |
| Component Type | Protein |
| Sequence Length | 245 aa |
tRNA (guanine-N(1)-)-methyltransferase
Review this target as tRNA (guanine-N(1)-)-methyltransferase, mapped to UniProt Q2FZ43. Sequence length is 245 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4517402 | 5.51 | Kd | 3100.0 | Preclinical |
| CHEMBL418052 | 5.48 | Kd | 3300.0 | Preclinical |
| CHEMBL2431997 | 4.56 | Kd | 27500.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 4 | 3 | 5.2 |