Skip to main content
Free research Free research Free target review with research home and workspace preview
Quick search ChEMBL 36
Loading Target Snapshot...
Querying ChEMBL database. This may take a few seconds.
Target Snapshot

CHEMBL4523938 Target Snapshot

Fucose-binding lectin PA-IIL · SINGLE PROTEIN · Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM14847 / LMG 12228 / 1C / PRS 101 / PAO1)

77Compounds
39Assays
0Approved Drugs
170.0Activities
Free Research Context

Research home keeps recent targets

This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.

Navigation

Switch target

Move to another high-traffic target or paste a specific ChEMBL target ID.

Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt Q9HYN5. Use UniProt Q9HYN5 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt Q9HYN5 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Fucose-binding lectin PA-IIL as ChEMBL target CHEMBL4523938, mapped to UniProt Q9HYN5. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Fucose-binding lectin PA-IIL
SINGLE PROTEIN · Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM14847 / LMG 12228 / 1C / PRS 101 / PAO1)
As of 2026-09-14
ChEMBL target ID
CHEMBL4523938
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
Q9HYN5
Fucose-binding lectin PA-IIL
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Fucose-binding lectin PA-IIL is the right protein anchor across sources, using UniProt Q9HYN5 as the stable mapping.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

Jump to Disease Context
Need a meeting-ready explanation of why this target matters?
Evidence Card
Review-ready rationale with source-aware context

Open the one-page evidence card when you want the rationale, activity base, and attribution together.

Open Review-ready Card
Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelFucose-binding lectin PA-IIL
UniProt AccessionQ9HYN5
Component TypeProtein
Sequence Length115 aa

Fucose-binding lectin PA-IIL

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Fucose-binding lectin PA-IIL, mapped to UniProt Q9HYN5. Sequence length is 115 aa.

Mapped IDQ9HYN5
Review nameFucose-binding lectin PA-IIL
OrganismPseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Clinical Profile

Clinical Phase Distribution

1
Phase III
1
Phase II
Assay Mix

Activity Type Distribution

IC50149.0
KD21.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL5176327 7.07 IC50 85.0 Preclinical
CHEMBL5188892 7.06 IC50 88.0 Preclinical
CHEMBL5177736 7.04 IC50 92.0 Preclinical
CHEMBL5205246 6.96 IC50 110.0 Preclinical
CHEMBL5192823 6.92 IC50 120.0 Preclinical
CHEMBL5195342 6.91 IC50 122.0 Preclinical
CHEMBL5189845 6.89 IC50 130.0 Preclinical
CHEMBL5208230 6.86 IC50 138.0 Preclinical
CHEMBL3218456 6.85 IC50 140.0 Preclinical
CHEMBL4550640 6.85 IC50 140.0 Preclinical
Distribution

pChEMBL Value Distribution

27
5.0
47
5.5
39
6.0
28
6.5
3
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

39
Total Assays
81
Tested Compounds
1
Assay Types
Binding — 39 assays, 81 compounds
BAO Format Assays Compounds Avg pChEMBL
single protein format 24 48 5.7
assay format 15 33 6.0

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine