Use UniProt Q8CM62 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL4523939 Target Snapshot
Sortase A · SINGLE PROTEIN · Streptococcus mutans
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As of 2026-09-14Protein identity stays anchored to UniProt Q8CM62. Use UniProt Q8CM62 as the stable identity anchor, then attach disease evidence before program review.
Sortase
Review this target as Sortase A, mapped to UniProt Q8CM62. ChEMBL maps the protein component as Sortase. Sequence length is 246 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Sortase A as ChEMBL target CHEMBL4523939, mapped to UniProt Q8CM62. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Sortase A is the right protein anchor across sources, using UniProt Q8CM62 as the stable mapping.
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Open Review-ready CardBasic Information
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| Preferred Name | Sortase A |
| Target Type | SINGLE PROTEIN |
| Organism | Streptococcus mutans |
| UniProt | Q8CM62 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Sortase |
| UniProt Accession | Q8CM62 |
| Component Type | Protein |
| Sequence Length | 246 aa |
Sortase
How to read this target
Review this target as Sortase A, mapped to UniProt Q8CM62. ChEMBL maps the protein component as Sortase. Sequence length is 246 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL7976 | 5.3 | IC50 | 5000.0 | Preclinical |
| CHEMBL140 | 4.99 | IC50 | 10200.0 | Clinical |
| CHEMBL28626 | 4.57 | IC50 | 27200.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 3 assays, 3 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 2 | 3 | 4.9 |
| assay format | 1 | 0 | — |