Nonstructural protein 3 · SINGLE PROTEIN · Zika virus
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As of 2026-09-14Protein identity stays anchored to UniProt A0A024AXB9. Use UniProt A0A024AXB9 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt A0A024AXB9 as the stable identity anchor, then attach disease evidence before program review.
Nonstructural protein 3
Review this target as Nonstructural protein 3, mapped to UniProt A0A024AXB9. Sequence length is 66 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Nonstructural protein 3 as ChEMBL target CHEMBL4523954, mapped to UniProt A0A024AXB9. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Nonstructural protein 3 |
| Target Type | SINGLE PROTEIN |
| Organism | Zika virus |
| UniProt | A0A024AXB9 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Nonstructural protein 3 |
| UniProt Accession | A0A024AXB9 |
| Component Type | Protein |
| Sequence Length | 66 aa |
Nonstructural protein 3
Review this target as Nonstructural protein 3, mapped to UniProt A0A024AXB9. Sequence length is 66 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5267698 | 8.77 | Ki | 1.7 | Preclinical |
| CHEMBL4589938 | 8.3 | Kd | 5.0 | Preclinical |
| CHEMBL4555617 | 8.1 | Kd | 8.0 | Preclinical |
| CHEMBL4452943 | 8.05 | Kd | 9.0 | Preclinical |
| CHEMBL4454475 | 8.05 | Kd | 9.0 | Preclinical |
| CHEMBL5604470 | 8.0 | IC50 | 10.0 | Preclinical |
| CHEMBL5604216 | 7.89 | IC50 | 13.0 | Preclinical |
| CHEMBL5604355 | 7.89 | IC50 | 13.0 | Preclinical |
| CHEMBL5604627 | 7.89 | IC50 | 13.0 | Preclinical |
| CHEMBL5605274 | 7.89 | IC50 | 13.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 26 | 228 | 5.5 |
| single protein format | 17 | 29 | 6.2 |
| cell-based format | 15 | 21 | 5.6 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 5 | 1,088 | 5.6 |