Programmed cell death protein 1/Programmed cell death 1 ligand 1 · PROTEIN COMPLEX · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q15116. Use UniProt Q15116 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q15116 as the stable identity anchor, then attach disease evidence before program review.
Programmed cell death protein 1
Review this target as Programmed cell death protein 1/Programmed cell death 1 ligand 1, mapped to UniProt Q15116. ChEMBL maps the protein component as Programmed cell death protein 1. Sequence length is 288 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Programmed cell death protein 1/Programmed cell death 1 ligand 1 as ChEMBL target CHEMBL4523993, mapped to UniProt Q15116. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Programmed cell death protein 1/Programmed cell death 1 ligand 1 is the right protein anchor across sources, using UniProt Q15116 as the stable mapping.
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| Preferred Name | Programmed cell death protein 1/Programmed cell death 1 ligand 1 |
| Target Type | PROTEIN COMPLEX |
| Organism | Homo sapiens |
| UniProt | Q15116 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Programmed cell death protein 1 |
| UniProt Accession | Q15116 |
| Component Type | Protein |
| Sequence Length | 288 aa |
Programmed cell death protein 1
Review this target as Programmed cell death protein 1/Programmed cell death 1 ligand 1, mapped to UniProt Q15116. ChEMBL maps the protein component as Programmed cell death protein 1. Sequence length is 288 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5411833 | 11.0 | IC50 | 0.01 | Preclinical |
| CHEMBL6041367 | 10.49 | IC50 | 0.032 | Preclinical |
| CHEMBL5816891 | 10.47 | IC50 | 0.034 | Preclinical |
| CHEMBL5182195 | 10.4 | IC50 | 0.04 | Preclinical |
| CHEMBL6061706 | 10.4 | IC50 | 0.04 | Preclinical |
| CHEMBL4865838 | 10.29 | IC50 | 0.051 | Preclinical |
| CHEMBL4862360 | 10.24 | IC50 | 0.058 | Preclinical |
| CHEMBL5743690 | 10.22 | IC50 | 0.06 | Preclinical |
| CHEMBL5777528 | 10.22 | IC50 | 0.06 | Preclinical |
| CHEMBL5831012 | 10.22 | IC50 | 0.06 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| protein complex format | 194 | 2,826 | 8.3 |
| cell-based format | 69 | 381 | 7.4 |
| assay format | 22 | 384 | 7.7 |
| tissue-based format | 11 | 0 | — |