TRAF2 and NCK-interacting protein kinase · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt Q9UKE5. Use UniProt Q9UKE5 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9UKE5 as the stable identity anchor, then attach disease evidence before program review.
TRAF2 and NCK-interacting protein kinase
Review this target as TRAF2 and NCK-interacting protein kinase, mapped to UniProt Q9UKE5. Sequence length is 1360 aa.
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This review treats TRAF2 and NCK-interacting protein kinase as ChEMBL target CHEMBL4527, mapped to UniProt Q9UKE5. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | TRAF2 and NCK-interacting protein kinase |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9UKE5 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | TRAF2 and NCK-interacting protein kinase |
| UniProt Accession | Q9UKE5 |
| Component Type | Protein |
| Sequence Length | 1360 aa |
TRAF2 and NCK-interacting protein kinase
Review this target as TRAF2 and NCK-interacting protein kinase, mapped to UniProt Q9UKE5. Sequence length is 1360 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4760558 | 9.92 | IC50 | 0.12 | Preclinical |
| CHEMBL4749291 | 9.89 | IC50 | 0.13 | Preclinical |
| CHEMBL4762464 | 9.74 | IC50 | 0.18 | Preclinical |
| CHEMBL4759123 | 9.72 | IC50 | 0.19 | Preclinical |
| CHEMBL4744045 | 9.68 | IC50 | 0.21 | Preclinical |
| CHEMBL4751494 | 9.68 | IC50 | 0.21 | Preclinical |
| CHEMBL4788405 | 9.66 | IC50 | 0.22 | Preclinical |
| CHEMBL4788976 | 9.66 | IC50 | 0.22 | Preclinical |
| CHEMBL4797452 | 9.64 | IC50 | 0.23 | Preclinical |
| CHEMBL4791330 | 9.6 | IC50 | 0.25 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 169 | 476 | 7.3 |
| cell-based format | 38 | 20 | 6.4 |
| assay format | 21 | 2 | 7.5 |
| subcellular format | 15 | 27 | 6.4 |
| tissue-based format | 1 | 0 | — |