Amine oxidase [copper-containing] 3 · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-13Protein identity stays anchored to UniProt O08590. Use UniProt O08590 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O08590 as the stable identity anchor, then attach disease evidence before program review.
Amine oxidase [copper-containing] 3
Review this target as Amine oxidase [copper-containing] 3, mapped to UniProt O08590. Sequence length is 763 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Amine oxidase [copper-containing] 3 as ChEMBL target CHEMBL4592, mapped to UniProt O08590. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Amine oxidase [copper-containing] 3 |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | O08590 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Amine oxidase [copper-containing] 3 |
| UniProt Accession | O08590 |
| Component Type | Protein |
| Sequence Length | 763 aa |
Amine oxidase [copper-containing] 3
Review this target as Amine oxidase [copper-containing] 3, mapped to UniProt O08590. Sequence length is 763 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL6003467 | 9.4 | IC50 | 0.4 | Preclinical |
| CHEMBL5892320 | 9.28 | IC50 | 0.53 | Preclinical |
| CHEMBL5741090 | 9.22 | IC50 | 0.6 | Preclinical |
| CHEMBL5852067 | 9.15 | IC50 | 0.7 | Preclinical |
| CHEMBL5896098 | 9.15 | IC50 | 0.7 | Preclinical |
| CHEMBL5801555 | 9.1 | IC50 | 0.8 | Preclinical |
| CHEMBL5973658 | 9.1 | IC50 | 0.8 | Preclinical |
| CHEMBL5816555 | 9.09 | IC50 | 0.81 | Preclinical |
| CHEMBL5901572 | 9.05 | IC50 | 0.9 | Preclinical |
| CHEMBL5937390 | 9.05 | IC50 | 0.9 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 8 | 8 | 6.2 |
| cell-based format | 5 | 34 | 6.5 |
| assay format | 4 | 109 | 8.4 |
| cell-free format | 1 | 3 | 5.5 |
| tissue-based format | 1 | 1 | 5.2 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 1 | 8.3 |