Complement C1r subcomponent · SINGLE PROTEIN · Homo sapiens
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt P00736. Use UniProt P00736 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P00736 as the stable identity anchor, then attach disease evidence before program review.
Complement C1r subcomponent
Review this target as Complement C1r subcomponent, mapped to UniProt P00736. Sequence length is 705 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Complement C1r subcomponent as ChEMBL target CHEMBL4611, mapped to UniProt P00736. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Complement C1r subcomponent is the right protein anchor across sources, using UniProt P00736 as the stable mapping.
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| Preferred Name | Complement C1r subcomponent |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P00736 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Complement C1r subcomponent |
| UniProt Accession | P00736 |
| Component Type | Protein |
| Sequence Length | 705 aa |
Complement C1r subcomponent
Review this target as Complement C1r subcomponent, mapped to UniProt P00736. Sequence length is 705 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL10770 | 6.7 | IC50 | 200.0 | Preclinical |
| CHEMBL10312 | 6.4 | IC50 | 400.0 | Preclinical |
| CHEMBL10610 | 6.4 | IC50 | 400.0 | Preclinical |
| CHEMBL10569 | 6.3 | IC50 | 500.0 | Preclinical |
| CHEMBL4247936 | 6.22 | IC50 | 600.0 | Preclinical |
| CHEMBL10432 | 6.16 | IC50 | 700.0 | Preclinical |
| CHEMBL158926 | 6.16 | IC50 | 700.0 | Preclinical |
| CHEMBL166801 | 6.16 | IC50 | 700.0 | Preclinical |
| CHEMBL10065 | 6.1 | IC50 | 800.0 | Preclinical |
| CHEMBL10248 | 6.1 | IC50 | 800.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 27 | 59 | 5.2 |
| assay format | 1 | 1 | 4.9 |
| cell-based format | 1 | 0 | — |