Genome polyprotein · SINGLE PROTEIN · Hepatitis C virus genotype 1a (isolate 1) (HCV)
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt P26664. Use UniProt P26664 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P26664 as the stable identity anchor, then attach disease evidence before program review.
Genome polyprotein
Review this target as Genome polyprotein, mapped to UniProt P26664. Sequence length is 3011 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Genome polyprotein as ChEMBL target CHEMBL4620, mapped to UniProt P26664. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Genome polyprotein is the right protein anchor across sources, using UniProt P26664 as the stable mapping.
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| Preferred Name | Genome polyprotein |
| Target Type | SINGLE PROTEIN |
| Organism | Hepatitis C virus genotype 1a (isolate 1) (HCV) |
| UniProt | P26664 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Genome polyprotein |
| UniProt Accession | P26664 |
| Component Type | Protein |
| Sequence Length | 3011 aa |
Genome polyprotein
Review this target as Genome polyprotein, mapped to UniProt P26664. Sequence length is 3011 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3644888 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL3644893 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL3644896 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL3644908 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL3644933 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL3644934 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL3644898 | 8.52 | IC50 | 3.0 | Preclinical |
| CHEMBL3644924 | 8.52 | IC50 | 3.0 | Preclinical |
| CHEMBL3644884 | 8.4 | IC50 | 4.0 | Preclinical |
| CHEMBL3644895 | 8.4 | IC50 | 4.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 12 | 205 | 5.9 |
| assay format | 2 | 26 | 6.6 |