Sodium channel protein type 5 subunit alpha/beta-1/beta-2 · PROTEIN COMPLEX · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q14524. Use UniProt Q14524 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q14524 as the stable identity anchor, then attach disease evidence before program review.
Sodium channel protein type 5 subunit alpha
Review this target as Sodium channel protein type 5 subunit alpha/beta-1/beta-2, mapped to UniProt Q14524. ChEMBL maps the protein component as Sodium channel protein type 5 subunit alpha. Sequence length is 2016 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Sodium channel protein type 5 subunit alpha/beta-1/beta-2 as ChEMBL target CHEMBL4630763, mapped to UniProt Q14524. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Sodium channel protein type 5 subunit alpha/beta-1/beta-2 is the right protein anchor across sources, using UniProt Q14524 as the stable mapping.
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| Preferred Name | Sodium channel protein type 5 subunit alpha/beta-1/beta-2 |
| Target Type | PROTEIN COMPLEX |
| Organism | Homo sapiens |
| UniProt | Q14524 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Sodium channel protein type 5 subunit alpha |
| UniProt Accession | Q14524 |
| Component Type | Protein |
| Sequence Length | 2016 aa |
Sodium channel protein type 5 subunit alpha
Review this target as Sodium channel protein type 5 subunit alpha/beta-1/beta-2, mapped to UniProt Q14524. ChEMBL maps the protein component as Sodium channel protein type 5 subunit alpha. Sequence length is 2016 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3657855 | 7.29 | IC50 | 51.0 | Preclinical |
| CHEMBL5094715 | 6.26 | IC50 | 551.0 | Preclinical |
| CHEMBL5276801 | 4.85 | IC50 | 14000.0 | Preclinical |
| CHEMBL5286433 | 4.85 | IC50 | 14000.0 | Preclinical |
| CHEMBL5286829 | 4.85 | IC50 | 14000.0 | Preclinical |
| CHEMBL5283939 | 4.64 | IC50 | 23000.0 | Preclinical |
| CHEMBL5270366 | 4.57 | IC50 | 27000.0 | Preclinical |
| CHEMBL4632675 | 4.55 | IC50 | 28000.0 | Preclinical |
| CHEMBL5286125 | 4.54 | IC50 | 29000.0 | Preclinical |
| CHEMBL5288162 | 4.51 | IC50 | 31000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 7 | 4.2 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 18 | 4.8 |