Complement factor B · SINGLE PROTEIN · Mus musculus
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As of 2026-09-13Protein identity stays anchored to UniProt P04186. Use UniProt P04186 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P04186 as the stable identity anchor, then attach disease evidence before program review.
Complement factor B
Review this target as Complement factor B, mapped to UniProt P04186. Sequence length is 761 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Complement factor B as ChEMBL target CHEMBL4630808, mapped to UniProt P04186. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Complement factor B is the right protein anchor across sources, using UniProt P04186 as the stable mapping.
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| Preferred Name | Complement factor B |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | P04186 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Complement factor B |
| UniProt Accession | P04186 |
| Component Type | Protein |
| Sequence Length | 761 aa |
Complement factor B
Review this target as Complement factor B, mapped to UniProt P04186. Sequence length is 761 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4639592 | 7.1 | IC50 | 80.0 | Preclinical |
| CHEMBL4594448 | 6.96 | IC50 | 110.0 | Approved |
| CHEMBL4641109 | 6.92 | IC50 | 120.0 | Preclinical |
| CHEMBL4644208 | 6.92 | IC50 | 120.0 | Preclinical |
| CHEMBL4632794 | 6.82 | IC50 | 150.0 | Preclinical |
| CHEMBL4646504 | 6.8 | IC50 | 160.0 | Preclinical |
| CHEMBL4644994 | 5.64 | IC50 | 2280.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-free format | 1 | 7 | 6.7 |