Sterol regulatory element-binding protein 1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P36956. Use UniProt P36956 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P36956 as the stable identity anchor, then attach disease evidence before program review.
Sterol regulatory element-binding protein 1
Review this target as Sterol regulatory element-binding protein 1, mapped to UniProt P36956. Sequence length is 1147 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Sterol regulatory element-binding protein 1 as ChEMBL target CHEMBL4630818, mapped to UniProt P36956. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Sterol regulatory element-binding protein 1 is the right protein anchor across sources, using UniProt P36956 as the stable mapping.
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| Preferred Name | Sterol regulatory element-binding protein 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P36956 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Sterol regulatory element-binding protein 1 |
| UniProt Accession | P36956 |
| Component Type | Protein |
| Sequence Length | 1147 aa |
Sterol regulatory element-binding protein 1
Review this target as Sterol regulatory element-binding protein 1, mapped to UniProt P36956. Sequence length is 1147 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL62136 | 7.7 | EC50 | 20.0 | Preclinical |
| CHEMBL5597982 | 6.89 | EC50 | 130.0 | Preclinical |
| CHEMBL5590706 | 6.72 | EC50 | 190.0 | Preclinical |
| CHEMBL5596248 | 6.72 | EC50 | 190.0 | Preclinical |
| CHEMBL5597153 | 6.62 | EC50 | 240.0 | Preclinical |
| CHEMBL5596815 | 6.51 | EC50 | 310.0 | Preclinical |
| CHEMBL5596386 | 6.24 | EC50 | 570.0 | Preclinical |
| CHEMBL1824673 | 6.16 | IC50 | 700.0 | Preclinical |
| CHEMBL4851466 | 6.14 | IC50 | 722.7 | Preclinical |
| CHEMBL5598250 | 6.11 | EC50 | 770.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 12 | 28 | 5.8 |
| single protein format | 2 | 3 | 5.5 |