Skip to main content
Free research Free research Free target review with research home and workspace preview
Quick search ChEMBL 36
Loading Target Snapshot...
Querying ChEMBL database. This may take a few seconds.
Target Snapshot

CHEMBL4630897 Target Snapshot

RNA-directed RNA polymerase L · SINGLE PROTEIN · Human respiratory syncytial virus A

0Compounds
0Assays
0Approved Drugs
0Activities
Free Research Context

Research home keeps recent targets

This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.

Navigation

Switch target

Move to another high-traffic target or paste a specific ChEMBL target ID.

Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

RNA-directed RNA polymerase L shows clinical signal disease relevance led by Respiratory Syncytial Virus Infection. 2 linked drugs keep the current disease frame grounded. Protein identity stays anchored to UniProt P28887. Start with Respiratory Syncytial Virus Infection, then reuse UniProt P28887 as the stable protein anchor across project notes and exports.

Review focus
Review-ready target frame

Start with Respiratory Syncytial Virus Infection, then reuse UniProt P28887 as the stable protein anchor across project notes and exports.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14 2 linked drugs
Open source guide
Disease program
Respiratory Syncytial Virus Infection

RNA-directed RNA polymerase L shows clinical signal disease relevance led by Respiratory Syncytial Virus Infection. 2 linked drugs remain visible in the same block.

Start review with Respiratory Syncytial Virus Infection because it currently carries clinical signal support. Linked drugs include LUMICITABINE, PC-786. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.

Disease source · ChEMBL drug mechanism + indication proxy
Clinical signal Open Targets-ready proxy 2 linked drugs
Open disease block
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats RNA-directed RNA polymerase L as ChEMBL target CHEMBL4630897, mapped to UniProt P28887. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
RNA-directed RNA polymerase L
SINGLE PROTEIN · Human respiratory syncytial virus A
As of 2026-09-14
ChEMBL target ID
CHEMBL4630897
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
P28887
RNA-directed RNA polymerase L
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether RNA-directed RNA polymerase L is the right protein anchor across sources, using UniProt P28887 as the stable mapping.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need to confirm why Respiratory Syncytial Virus Infection is currently framed as clinical signal support. It currently carries 2 linked drugs in the same disease frame.

Jump to Disease Context
Need a meeting-ready explanation of why this target matters?
Evidence Card
Review-ready rationale with source-aware context

Open the one-page evidence card when you want the rationale, activity base, and attribution together.

Open Review-ready Card
Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelRNA-directed RNA polymerase L
UniProt AccessionP28887
Component TypeProtein
Sequence Length2165 aa

RNA-directed RNA polymerase L

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as RNA-directed RNA polymerase L, mapped to UniProt P28887. Sequence length is 2165 aa.

Mapped IDP28887
Review nameRNA-directed RNA polymerase L
OrganismHuman respiratory syncytial virus A
Disease Relevance

Disease Relevance & Evidence Level

Open Targets-ready disease context using the current target-indication evidence contract.

Clinical signal Open Targets-ready proxy

RNA-directed RNA polymerase L shows clinical signal disease relevance led by Respiratory Syncytial Virus Infection.

Clinical signal Phase II
Respiratory Syncytial Virus Infection
2 linked drugs · 2 direct · 2 efficacy
Linked drugLUMICITABINE
Linked drugPC-786
Source · ChEMBL drug mechanism + indication proxy
Review Cue

How to read disease relevance

Start review with Respiratory Syncytial Virus Infection because it currently carries clinical signal support. Linked drugs include LUMICITABINE, PC-786. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.

Lead diseaseRespiratory Syncytial Virus Infection
Strongest levelClinical signal
Block modeOpen Targets-ready proxy
Distribution

pChEMBL Value Distribution

0
5.0
0
5.5
0
6.0
0
6.5
0
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Source · ChEMBL 36 via Core Engine