Potassium voltage-gated channel subfamily A member 3 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P22001. Use UniProt P22001 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P22001 as the stable identity anchor, then attach disease evidence before program review.
Potassium voltage-gated channel subfamily A member 3
Review this target as Potassium voltage-gated channel subfamily A member 3, mapped to UniProt P22001. Sequence length is 575 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Potassium voltage-gated channel subfamily A member 3 as ChEMBL target CHEMBL4633, mapped to UniProt P22001. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Potassium voltage-gated channel subfamily A member 3 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P22001 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Potassium voltage-gated channel subfamily A member 3 |
| UniProt Accession | P22001 |
| Component Type | Protein |
| Sequence Length | 575 aa |
Potassium voltage-gated channel subfamily A member 3
Review this target as Potassium voltage-gated channel subfamily A member 3, mapped to UniProt P22001. Sequence length is 575 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3609094 | 10.92 | IC50 | 0.012 | Preclinical |
| CHEMBL3609093 | 10.8 | IC50 | 0.016 | Preclinical |
| CHEMBL3609263 | 10.74 | IC50 | 0.018 | Preclinical |
| CHEMBL3609033 | 10.7 | IC50 | 0.02 | Preclinical |
| CHEMBL3608994 | 10.64 | IC50 | 0.023 | Preclinical |
| CHEMBL3609063 | 10.64 | IC50 | 0.023 | Preclinical |
| CHEMBL3609272 | 10.64 | IC50 | 0.023 | Preclinical |
| CHEMBL3609265 | 10.54 | IC50 | 0.029 | Preclinical |
| CHEMBL3609095 | 10.51 | IC50 | 0.031 | Preclinical |
| CHEMBL3609266 | 10.51 | IC50 | 0.031 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 54 | 361 | 7.2 |
| single protein format | 7 | 252 | 8.6 |
| assay format | 4 | 45 | 5.9 |
| cell membrane format | 2 | 11 | 7.1 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 6 | 101 | 6.7 |
| assay format | 3 | 21 | 6.4 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 1 | 0 | — |