Proline--tRNA ligase, cytoplasmic · SINGLE PROTEIN · Candida albicans
This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.
Move to another high-traffic target or paste a specific ChEMBL target ID.
Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt P78600. Use UniProt P78600 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P78600 as the stable identity anchor, then attach disease evidence before program review.
Proline--tRNA ligase, cytoplasmic
Review this target as Proline--tRNA ligase, cytoplasmic, mapped to UniProt P78600. Sequence length is 575 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Proline--tRNA ligase, cytoplasmic as ChEMBL target CHEMBL4636, mapped to UniProt P78600. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
Choose the first block or source based on the question you are trying to answer.
Start here when your first question is whether Proline--tRNA ligase, cytoplasmic is the right protein anchor across sources, using UniProt P78600 as the stable mapping.
Jump to Protein ContextUse this block first when you need the strongest disease program and evidence level in one place.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
Open Review-ready CardVerify identity, organism, and the fastest next research jumps from the same page.
| Preferred Name | Proline--tRNA ligase, cytoplasmic |
| Target Type | SINGLE PROTEIN |
| Organism | Candida albicans |
| UniProt | P78600 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Proline--tRNA ligase, cytoplasmic |
| UniProt Accession | P78600 |
| Component Type | Protein |
| Sequence Length | 575 aa |
Proline--tRNA ligase, cytoplasmic
Review this target as Proline--tRNA ligase, cytoplasmic, mapped to UniProt P78600. Sequence length is 575 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL357355 | 8.3 | IC50 | 5.0 | Preclinical |
| CHEMBL357572 | 7.72 | IC50 | 19.0 | Preclinical |
| CHEMBL345331 | 7.7 | IC50 | 20.0 | Preclinical |
| CHEMBL150488 | 7.6 | IC50 | 25.0 | Preclinical |
| CHEMBL153347 | 7.6 | IC50 | 25.0 | Preclinical |
| CHEMBL153238 | 7.58 | IC50 | 26.0 | Preclinical |
| CHEMBL151039 | 7.52 | IC50 | 30.0 | Preclinical |
| CHEMBL153295 | 7.28 | IC50 | 53.0 | Preclinical |
| CHEMBL150266 | 7.16 | IC50 | 70.0 | Preclinical |
| CHEMBL346646 | 6.92 | IC50 | 120.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 1 | 27 | 6.3 |