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Target Snapshot

CHEMBL4649981 Target Snapshot

Wolbachia pipientis · ORGANISM · Wolbachia pipientis

Back to Search Search this target Browse approvals Evidence Card
48,555Compounds
1Assays
0Approved Drugs
336.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Wolbachia pipientis as ChEMBL target CHEMBL4649981. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Wolbachia pipientis
ORGANISM · Wolbachia pipientis
As of 2026-09-14
ChEMBL target ID
CHEMBL4649981
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Wolbachia pipientis still has a stable protein naming contract across sources.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NameWolbachia pipientis
Target TypeORGANISM
OrganismWolbachia pipientis
ChEMBL ↗ NCBI Taxonomy ↗

Next Actions

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelWolbachia pipientis
UniProt AccessionN/A

Wolbachia pipientis

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as Wolbachia pipientis.

Review nameWolbachia pipientis
OrganismWolbachia pipientis
Assay Mix

Activity Type Distribution

IC50336.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL3480436 7.08 IC50 84.08 Preclinical
CHEMBL3457622 6.47 IC50 339.79 Preclinical
CHEMBL3502891 6.47 IC50 336.68 Preclinical
CHEMBL3452782 6.46 IC50 348.71 Preclinical
CHEMBL3500026 6.33 IC50 462.38 Preclinical
CHEMBL3499888 6.28 IC50 526.16 Preclinical
CHEMBL3478581 6.25 IC50 562.42 Preclinical
CHEMBL3481537 6.25 IC50 556.09 Preclinical
CHEMBL3499995 6.17 IC50 677.88 Preclinical
CHEMBL3454186 6.16 IC50 698.19 Preclinical
Distribution

pChEMBL Value Distribution

88
5.0
59
5.5
18
6.0
1
6.5
1
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

1
Total Assays
92
Tested Compounds
1
Assay Types
Functional — 1 assays, 92 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 1 92 5.5

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine