Somatostatin receptor type 1 · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt P28646. Use UniProt P28646 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P28646 as the stable identity anchor, then attach disease evidence before program review.
Somatostatin receptor type 1
Review this target as Somatostatin receptor type 1, mapped to UniProt P28646. Sequence length is 391 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Somatostatin receptor type 1 as ChEMBL target CHEMBL4652, mapped to UniProt P28646. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Somatostatin receptor type 1 is the right protein anchor across sources, using UniProt P28646 as the stable mapping.
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| Preferred Name | Somatostatin receptor type 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P28646 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Somatostatin receptor type 1 |
| UniProt Accession | P28646 |
| Component Type | Protein |
| Sequence Length | 391 aa |
Somatostatin receptor type 1
Review this target as Somatostatin receptor type 1, mapped to UniProt P28646. Sequence length is 391 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL254500 | 9.69 | Kd | 0.2042 | Preclinical |
| CHEMBL401290 | 9.67 | Kd | 0.2138 | Preclinical |
| CHEMBL252032 | 9.62 | Kd | 0.2399 | Preclinical |
| CHEMBL254505 | 9.55 | Kd | 0.2818 | Preclinical |
| CHEMBL540705 | 9.49 | Kd | 0.3236 | Preclinical |
| CHEMBL251835 | 9.43 | Kd | 0.3715 | Preclinical |
| CHEMBL252033 | 9.43 | Kd | 0.3715 | Preclinical |
| CHEMBL401309 | 9.42 | Kd | 0.3802 | Preclinical |
| CHEMBL254499 | 9.41 | Kd | 0.389 | Preclinical |
| CHEMBL398526 | 9.41 | Kd | 0.389 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 3 | 93 | 7.5 |
| cell membrane format | 1 | 25 | 8.4 |
| single protein format | 1 | 33 | 8.2 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 0 | — |