Dipeptidyl peptidase 4 · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-13Protein identity stays anchored to UniProt P14740. Use UniProt P14740 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P14740 as the stable identity anchor, then attach disease evidence before program review.
Dipeptidyl peptidase 4
Review this target as Dipeptidyl peptidase 4, mapped to UniProt P14740. Sequence length is 767 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Dipeptidyl peptidase 4 as ChEMBL target CHEMBL4653, mapped to UniProt P14740. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Dipeptidyl peptidase 4 is the right protein anchor across sources, using UniProt P14740 as the stable mapping.
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| Preferred Name | Dipeptidyl peptidase 4 |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P14740 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Dipeptidyl peptidase 4 |
| UniProt Accession | P14740 |
| Component Type | Protein |
| Sequence Length | 767 aa |
Dipeptidyl peptidase 4
Review this target as Dipeptidyl peptidase 4, mapped to UniProt P14740. Sequence length is 767 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL445437 | 9.89 | IC50 | 0.13 | Preclinical |
| CHEMBL194717 | 9.82 | IC50 | 0.15 | Preclinical |
| CHEMBL370540 | 9.77 | IC50 | 0.17 | Preclinical |
| CHEMBL370046 | 9.77 | IC50 | 0.17 | Preclinical |
| CHEMBL456420 | 9.77 | IC50 | 0.17 | Preclinical |
| CHEMBL2147704 | 9.74 | IC50 | 0.18 | Preclinical |
| CHEMBL2147703 | 9.72 | IC50 | 0.19 | Preclinical |
| CHEMBL433811 | 9.62 | IC50 | 0.24 | Preclinical |
| CHEMBL371143 | 9.59 | IC50 | 0.26 | Preclinical |
| CHEMBL195420 | 9.57 | IC50 | 0.27 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 23 | 96 | 7.2 |
| cell-free format | 14 | 116 | 7.8 |
| organism-based format | 4 | 0 | — |
| microsome format | 2 | 0 | — |
| assay format | 1 | 0 | — |
| tissue-based format | 1 | 3 | 4.2 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| organism-based format | 10 | 0 | — |
| assay format | 7 | 0 | — |
| cell-free format | 7 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-free format | 1 | 0 | — |
| single protein format | 1 | 0 | — |