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Evidence Snapshot

IL36 receptor

CHEMBL4665591 PROTEIN COMPLEX Homo sapiens
Source Header

ChEMBL 36 via Core Engine

Target Snapshot 2026-09-13T17:02:42Z
Source · ChEMBL 36 via Core Engine
ChEMBL ChEMBL 36 CHEMBL4665591
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats IL36 receptor as ChEMBL target CHEMBL4665591, mapped to UniProt Q9HB29. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
IL36 receptor
PROTEIN COMPLEX · Homo sapiens
As of 2026-09-13
ChEMBL target ID
CHEMBL4665591
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
UniProt accession
Q9HB29
Interleukin-1 receptor-like 2
UniProt accession via ChEMBL component mapping As of 2026-09-13
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Review-ready Target Rationale

Why IL36 receptor matters

As of 2026-09-13

IL36 receptor is reviewed as Interleukin-1 receptor-like 2 (UniProt Q9HB29); IL36 receptor shows approved-linked disease relevance led by psoriasis. 5 more disease programs remain visible in the same review block.; 2 linked drugs keep this evidence frame grounded..

Protein context
Interleukin-1 receptor-like 2

Interleukin-1 receptor-like 2 Sequence length is 575 aa.

Review this target as IL36 receptor, mapped to UniProt Q9HB29. ChEMBL maps the protein component as Interleukin-1 receptor-like 2. Sequence length is 575 aa.

Protein source · UniProt accession via ChEMBL component mapping
UniProt Q9HB29 Protein
Disease context
psoriasis

IL36 receptor shows approved-linked disease relevance led by psoriasis. 5 more disease programs remain visible in the same review block. 2 linked drugs keep the rationale reviewable. 5 additional disease programs remain visible in the same card. Linked drugs include IMSIDOLIMAB, SPESOLIMAB.

Start review with psoriasis because it currently carries approved-linked support. Linked drugs include IMSIDOLIMAB, SPESOLIMAB. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.

ChEMBL target record
Approved-linked 2 linked drugs
Source Guidance

Start with the right source

Pick the first block or linked source that matches the review question in front of you.

Need the shortest review narrative first?
Review-ready Target Rationale
One-page rationale with as-of-date and attribution

Start with the review rationale when you need to explain why IL36 receptor matters before drilling into raw source blocks.

Jump to Review Rationale
Need stable protein naming or accession mapping?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Go back to the target snapshot when you need the naming and mapping contract behind UniProt Q9HB29, not just the summarized rationale.

Open Protein Context
Need disease fit or evidence level for program framing?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use the target snapshot disease block when you need to see why psoriasis is currently treated as approved-linked support.

Open Disease Context

Snapshot State

No project snapshot selected. Export uses the live evidence card state.

0
Total Compounds
0
Total Assays
0
Approved Drugs
-
Activity Types

pChEMBL Activity Distribution

← Target Page
Source Header

ChEMBL 36 via Core Engine

Target Snapshot 2026-09-13T17:02:42Z
Source · ChEMBL 36 via Core Engine
ChEMBL ChEMBL 36 CHEMBL4665591