Aspartyl/asparaginyl beta-hydroxylase · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt Q12797. Use UniProt Q12797 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q12797 as the stable identity anchor, then attach disease evidence before program review.
Aspartyl/asparaginyl beta-hydroxylase
Review this target as Aspartyl/asparaginyl beta-hydroxylase, mapped to UniProt Q12797. Sequence length is 758 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Aspartyl/asparaginyl beta-hydroxylase as ChEMBL target CHEMBL4680030, mapped to UniProt Q12797. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Aspartyl/asparaginyl beta-hydroxylase is the right protein anchor across sources, using UniProt Q12797 as the stable mapping.
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| Preferred Name | Aspartyl/asparaginyl beta-hydroxylase |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q12797 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Aspartyl/asparaginyl beta-hydroxylase |
| UniProt Accession | Q12797 |
| Component Type | Protein |
| Sequence Length | 758 aa |
Aspartyl/asparaginyl beta-hydroxylase
Review this target as Aspartyl/asparaginyl beta-hydroxylase, mapped to UniProt Q12797. Sequence length is 758 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL316034 | 7.7 | IC50 | 20.0 | Preclinical |
| CHEMBL5422782 | 7.3 | IC50 | 50.0 | Preclinical |
| CHEMBL5430087 | 6.96 | IC50 | 110.0 | Preclinical |
| CHEMBL3752910 | 6.64 | Kd | 227.22 | Preclinical |
| CHEMBL51483 | 6.6 | IC50 | 250.0 | Clinical |
| CHEMBL5429223 | 6.55 | IC50 | 280.0 | Preclinical |
| CHEMBL5425339 | 6.3 | IC50 | 500.0 | Preclinical |
| CHEMBL5415306 | 6.24 | IC50 | 580.0 | Preclinical |
| CHEMBL443684 | 6.1 | IC50 | 800.0 | Clinical |
| CHEMBL5428941 | 6.05 | IC50 | 900.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 7 | 22 | 5.7 |
| single protein format | 3 | 4 | 6.6 |
| cell-based format | 1 | 10 | 5.5 |