SLC34A2-ROS1 · CHIMERIC PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P08922. Use UniProt P08922 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P08922 as the stable identity anchor, then attach disease evidence before program review.
Proto-oncogene tyrosine-protein kinase ROS
Review this target as SLC34A2-ROS1, mapped to UniProt P08922. ChEMBL maps the protein component as Proto-oncogene tyrosine-protein kinase ROS. Sequence length is 2347 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats SLC34A2-ROS1 as ChEMBL target CHEMBL4680045, mapped to UniProt P08922. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether SLC34A2-ROS1 is the right protein anchor across sources, using UniProt P08922 as the stable mapping.
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| Preferred Name | SLC34A2-ROS1 |
| Target Type | CHIMERIC PROTEIN |
| Organism | Homo sapiens |
| UniProt | P08922 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Proto-oncogene tyrosine-protein kinase ROS |
| UniProt Accession | P08922 |
| Component Type | Protein |
| Sequence Length | 2347 aa |
Proto-oncogene tyrosine-protein kinase ROS
Review this target as SLC34A2-ROS1, mapped to UniProt P08922. ChEMBL maps the protein component as Proto-oncogene tyrosine-protein kinase ROS. Sequence length is 2347 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3286830 | 9.72 | IC50 | 0.19 | Approved |
| CHEMBL5712062 | 9.72 | IC50 | 0.19 | Preclinical |
| CHEMBL601719 | 7.29 | IC50 | 51.0 | Approved |
| CHEMBL1230609 | 7.0 | IC50 | 99.0 | Clinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 18 | 4 | 8.2 |