Use UniProt O97467 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL4697 Target Snapshot
Hexose transporter 1 · SINGLE PROTEIN · Plasmodium falciparum
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As of 2026-09-14Protein identity stays anchored to UniProt O97467. Use UniProt O97467 as the stable identity anchor, then attach disease evidence before program review.
Hexose transporter 1
Review this target as Hexose transporter 1, mapped to UniProt O97467. Sequence length is 504 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Hexose transporter 1 as ChEMBL target CHEMBL4697, mapped to UniProt O97467. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Hexose transporter 1 is the right protein anchor across sources, using UniProt O97467 as the stable mapping.
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Open Review-ready CardBasic Information
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| Preferred Name | Hexose transporter 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Plasmodium falciparum |
| UniProt | O97467 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Hexose transporter 1 |
| UniProt Accession | O97467 |
| Component Type | Protein |
| Sequence Length | 504 aa |
Hexose transporter 1
How to read this target
Review this target as Hexose transporter 1, mapped to UniProt O97467. Sequence length is 504 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL592105 | 7.46 | IC50 | 35.0 | Preclinical |
| CHEMBL4634177 | 7.26 | IC50 | 55.0 | Preclinical |
| CHEMBL4634839 | 7.26 | IC50 | 55.0 | Preclinical |
| CHEMBL4645191 | 7.26 | IC50 | 55.0 | Preclinical |
| CHEMBL4647311 | 7.26 | IC50 | 55.0 | Preclinical |
| CHEMBL4647586 | 7.26 | IC50 | 55.0 | Preclinical |
| CHEMBL5754009 | 7.26 | IC50 | 55.0 | Preclinical |
| CHEMBL5767973 | 7.26 | IC50 | 55.0 | Preclinical |
| CHEMBL5769176 | 7.26 | IC50 | 55.0 | Preclinical |
| CHEMBL5799651 | 7.26 | IC50 | 55.0 | Preclinical |
pChEMBL Value Distribution
Approved Drugs
Assay Landscape
Functional — 3 assays, 436 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 2 | 419 | 5.5 |
| cell-based format | 1 | 17 | 4.4 |
Binding — 2 assays, 63 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 4 | 5.1 |
| single protein format | 1 | 59 | 6.8 |